The postdoctoral scholar is responsible for independent and collaborative development, implementation, and analysis of scientific research in the discipline of molecular biology, cell culture, protein purification, crystallization, 3D structure determination and modeling, biochemical and biophysical protein characterization, high and low-throughput ligand screening for drug discovery, and manuscript preparation. Responsibilities include management of all aspects of structure and function of carbohydrate transporters, (important membrane proteins involved in cancer, diabetes and aging), glucose conjugation and transport of salicylic acid (with role in the defense of plants against pathogens), protein engineering, and drug discovery for cancer and diabetes treatment. The experiments involve molecular biology, membrane protein purification (from bacterial, insect and human cells), x-ray protein crystallography, small angle x-ray scattering, computational modeling, biochemical and biophysical protein characterization. The research is funded by the US National Institute of Health and we have international collaborators for the projects. We are looking for someone motivated to contribute to multiple projects and eager to be challenged. Duties include: hypothesis development, literature review, collection of pilot data, report writing, and supervising of undergraduate research students and graduate research students, overseeing data collection procedures, supervising experimental procedures, review of data for quality control, supervision of data entry/data analysis, analysis of research hypothesis using descriptive and multivariate statistics, and the development of independent and collaborative presentations and publications. Scholars are expected to demonstrate compliance with established guidelines and regulatory standards for research including biosafety, responsible conduct of research and human subjects training. Approximately 85% of the postdoctoral scholar's time will be devoted to planning and design of experiments and performing experiments. Approximately 15% of the postdoctoral scholar's time will be devoted to managing the day-to-day activity of undergraduate and graduate research students in the laboratory.
Special Instructions To Application:
To be considered for this position, all applicants must apply through PeopleAdmin and attach their CV or resume, cover letter and names and contact information of 3 references. Appointments are typically for a one-year period. Five years (typically five appointments of one year) is typically the maximum total period that any individual may serve as a Scholar. The University, in its sole discretion has the option to renew or extend any appointment, subject to the availability of funds, past performance evaluations and/or any other lawful reasons. For other information on the ECU Office of Postdoctoral Affairs, please visit our website at: https://rede.ecu.edu/postdoctoral/
English Proficiency Excellent written and oral communication skills Ph.D. in biochemistry, structural biology or related area
Full time or Part time: Full Time
Position Location (city): Greenville
Position Number: PDS-CHEM-10-18
Organizational Unit Overview:
Welcome to the East Carolina Diabetes and Obesity Institute (ECDOI) at East Carolina University. The ECDOI is an interdisciplinary research institute jointly supported by the Divisions of Health Sciences and Research & Graduate Studies.
The ECDOI is well known for cutting-edge collaborative research in several fields related to disorders of metabolism, including bariatric surgery, muscle insulin signaling/glucose transport, bioenergetics/exercise physiology, and pediatric healthy weight programs.
The mission of the East Carolina Diabetes and Obesity Institute is to develop, promote, facilitate, and support interdisciplinary basic and clinical research in disorders of metabolism including diabetes, cardiovascular disease, obesity, and cancer.
To be a national model for student success, public service and regional transformation, East Carolina University uses innovative learning strategies and delivery methods to maximize access; prepares students with the knowledge, skills and values to succeed in a global, multicultural society; develops tomorrow's leaders to serve and inspire positive change; discovers new knowledge and innovations to support a thriving future for eastern North Carolina and beyond; transforms health care, promotes wellness, and reduces health disparities; and improves qualify of life through cultural enrichment, academics, the arts, and athletics. We accomplish our mission through education, research, creative activities, and service while being good stewards of the resources entrusted to us. East Carolina University delivers on the promise of opportunity. We open doors. We improve lives. We transform the present, and we discover the future. In these ways and more, we serve our community, our state, our nation and our world as together we reach toward our greatest potential. Tomorrow starts here.